Cruising the nation’s legendary rivers and picturesque coastlines, guests will experience one comprehensive itinerary that links together many of American Cruise Lines’ most fascinating and popular cruises. Guests will explore 20 U.S. states aboard three small ships, traverse four U.S. time zones, and cruise coast to coast along four U.S. rivers for an unparalleled adventure.

Start your journey with the Columbia & Snake Rivers and three National Parks. Roll along the Mississippi River with Mark Twain and Elvis before venturing to explore the charming harbor towns of New England and New York during peak fall foliage season. Onboard, guests enjoy spacious staterooms, private balconies, elegant restaurants and casual cafes, multiple indoor and outdoor lounges including wide-open top decks for breathtaking views of the passing scenery.

All elements of the travel experience are fully curated, and all arrangements handled with the utmost care by the American Cruise Lines' dedicated travel team, ensuring guests have a seamless journey from beginning to end on this monumental U.S. River cruise.